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Vadim Viviani said: “Our best combination is much redder at 650 nanometers, three times brighter than natural luciferin and luciferase, and about 1,000 times brighter than the same luciferase using a commercially available analog,” External link

floridanewstimes Tuesday, March 30, 2021 2:48:00 PM CEST

Vadim Viviani said: "Red bioluminescence is preferred when imaging biological or pathological processes in mammalian tissues because hemoglobin, myoglobin and melanin absorb little long-wavelength light. Detection is best of all in the far red and near-infrared bands, but bioluminescent systems that naturally emit far red light don't exist," "Some genetically modified forms of luciferase and synthetic analogs of natural luciferins are produced commercially. In conjunction, they produce light at wavelengths as long as 700 nanometers, but the light produced by these artificial systems is generally much weaker and more short-lived than light from natural bioluminescent systems" External link

newsmedical Tuesday, March 30, 2021 6:53:00 AM CEST

Vadim Viviani said: "Our best combination produces far-red at 650 nanometers, three times brighter than natural luciferin and luciferase, and roughly 1,000 times brighter than the same luciferase with a commercial analog," "Besides the long-wavelength and intense brightness, our combination has better thermal stability and cell membrane penetrability. Above all, it produces more lasting continuous bioluminescence, taking at least an hour to decay and significantly facilitating the real-time imaging of biological and pathological processes" External link

newsmedical Tuesday, March 30, 2021 6:53:00 AM CEST

Vadim Viviani told: "We obtained a novel luciferin-luciferase system that produces far red light at the wavelength of 650 nanometers and emits the brightest bioluminescence ever reported in this part of the spectrum. It's a highly promising result for bioluminescence imaging of biological and pathological processes in mammalian tissues," External link

7thspace Monday, March 29, 2021 11:10:00 PM CEST

Vadim Viviani said: "Red bioluminescence is preferred when imaging biological or pathological processes in mammalian tissues because hemoglobin, myoglobin and melanin absorb little long-wavelength light. Detection is best of all in the far red and near-infrared bands, but bioluminescent systems that naturally emit far red light don't exist," "Some genetically modified forms of luciferase and synthetic analogs of natural luciferins are produced commercially. In conjunction, they produce light at wavelengths as long as 700 nanometers, but the light produced by these artificial systems is generally much weaker and more short-lived than light from natural bioluminescent systems" External link

7thspace Monday, March 29, 2021 11:10:00 PM CEST

Vadim Viviani said: "Our best combination produces far red at 650 nanometers, three times brighter than natural luciferin and luciferase, and roughly 1,000 times brighter than the same luciferase with a commercial analog," "Besides the long wavelength and intense brightness, our combination has better thermal stability and cell membrane penetrability. Above all, it produces more lasting continuous bioluminescence, taking at least an hour to decay and significantly facilitating the real-time imaging of biological and pathological processes" External link

7thspace Monday, March 29, 2021 11:10:00 PM CEST

Vadim Viviani told: "We obtained a novel luciferin-luciferase system that produces far red light at the wavelength of 650 nanometers and emits the brightest bioluminescence ever reported in this part of the spectrum. It's a highly promising result for bioluminescence imaging of biological and pathological processes in mammalian tissues," External link

eurekalert Monday, March 29, 2021 7:22:00 PM CEST

Vadim Viviani said: "Red bioluminescence is preferred when imaging biological or pathological processes in mammalian tissues because hemoglobin, myoglobin and melanin absorb little long-wavelength light. Detection is best of all in the far red and near-infrared bands, but bioluminescent systems that naturally emit far red light don't exist," "Some genetically modified forms of luciferase and synthetic analogs of natural luciferins are produced commercially. In conjunction, they produce light at wavelengths as long as 700 nanometers, but the light produced by these artificial systems is generally much weaker and more short-lived than light from natural bioluminescent systems" External link

eurekalert Monday, March 29, 2021 7:22:00 PM CEST

Vadim Viviani said: "Our best combination produces far red at 650 nanometers, three times brighter than natural luciferin and luciferase, and roughly 1,000 times brighter than the same luciferase with a commercial analog," "Besides the long wavelength and intense brightness, our combination has better thermal stability and cell membrane penetrability. Above all, it produces more lasting continuous bioluminescence, taking at least an hour to decay and significantly facilitating the real-time imaging of biological and pathological processes" External link

eurekalert Monday, March 29, 2021 7:22:00 PM CEST

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